Novel Synthetic Antagonists of Canonical Wnt Signaling Inhibit Colorectal Cancer Cell Growth
Abstract Canonical Wnt signaling is deregulated in several types of human cancer where it plays a central role in tumor cell growth and progression. Here we report the identification of 2 new small molecules that specifically inhibit canonical Wnt pathway at the level of the destruction complex. Spe...
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| Glavni autori: | , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | engleski |
| Izdano: |
2011
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| Online pristup: | https://doi.org/10.1158/0008-5472.can-10-1282 |
| Oznake: |
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