Mapping of the ligand-binding site on the b′ domain of human PDI: interaction with peptide ligands and the x-linker region
PDI (protein disulfide-isomerase) catalyses the formation of native disulfide bonds of secretory proteins in the endoplasmic reticulum. PDI consists of four thioredoxin-like domains, of which two contain redox-active catalytic sites (a and a'), and two do not (b and b'). The b' domain...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Englisch |
| Veröffentlicht: |
2009
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| Online-Zugang: | https://doi.org/10.1042/bj20090565 |
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