The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA
Three-dimensional topology of DNA in the cell nucleus provides a level of transcription regulation beyond the sequence of the linear DNA. To study the relationship between the transcriptional activity and the spatial environment of a gene, we used allele-specific chromosome conformation capture-on-c...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2011
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| Online Access: | https://doi.org/10.1101/gad.633311 http://genesdev.cshlp.org/content/25/13/1371.full.pdf |
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