Mycobacterium tuberculosis strains disrupted in mce3 and mce4 operons are attenuated in mice
The Mycobacterium tuberculosis genome contains four copies of an operon called mce (mce1-4). Previously we reported that M. tuberculosis disrupted in the mce1 operon is more virulent than wild-type M. tuberculosis in mice. We generated single deletion mutants in mce3 (Deltamce3) and mce4 (Deltamce4)...
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Hoofdauteurs: | , , , , , , , , , , , |
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Formaat: | Artigo |
Taal: | Engels |
Gepubliceerd in: |
2008
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Online toegang: | https://doi.org/10.1099/jmm.0.47454-0 |
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