Combined Influence of <i>LDLR</i> and <i>HMGCR</i> Sequence Variation on Lipid-Lowering Response to Simvastatin
Although statins are efficacious for lowering low-density lipoprotein cholesterol, there is wide interindividual variation in response. We tested the extent to which combined effects of common alleles of LDLR and HMGCR can contribute to this variability.Haplotypes in the LDLR 3'-untranslated re...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2010
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| Online Access: | https://doi.org/10.1161/atvbaha.110.203273 |
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