Combined Influence of <i>LDLR</i> and <i>HMGCR</i> Sequence Variation on Lipid-Lowering Response to Simvastatin

Combined Influence of <i>LDLR</i> and <i>HMGCR</i> Sequence Variation on Lipid-Lowering Response to Simvastatin

Although statins are efficacious for lowering low-density lipoprotein cholesterol, there is wide interindividual variation in response. We tested the extent to which combined effects of common alleles of LDLR and HMGCR can contribute to this variability.Haplotypes in the LDLR 3'-untranslated re...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Lara M. Mangravite, Marisa W. Medina, Jinrui Cui, Sheila Pressman, Joshua D. Smith, Mark J. Rieder, Xiuqing Guo, Deborah A. Nickerson, Jerome I. Rotter, Ronald M. Krauss
स्वरूप: Artigo
भाषा:अंग्रेज़ी
प्रकाशित: 2010
ऑनलाइन पहुंच:https://doi.org/10.1161/atvbaha.110.203273
टैग: टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

इंटरनेट

https://doi.org/10.1161/atvbaha.110.203273

समान संसाधन