Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug Design
Cysteine proteases of the papain superfamily are implicated in a number of cellular processes and are important virulence factors in the pathogenesis of parasitic disease. These enzymes have therefore emerged as promising targets for antiparasitic drugs. We report the crystal structures of three maj...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Αγγλικά |
Έκδοση: |
2009
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Διαθέσιμο Online: | https://doi.org/10.1074/jbc.m109.014340 http://www.jbc.org/article/S0021925818810444/pdf |
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