Selective Inhibition of Histone Deacetylases Sensitizes Malignant Cells to Death Receptor Ligands

Selective Inhibition of Histone Deacetylases Sensitizes Malignant Cells to Death Receptor Ligands

Abstract Evasion of death receptor ligand–induced apoptosis represents an important contributor to cancer development and progression. Therefore, molecules that restore sensitivity to death receptor stimuli would be important tools to better understand this biological pathway and potential leads for...

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Main Authors: Tabitha E. Wood, Shadi Dalili, Craig D. Simpson, Mahadeo A. Sukhai, Rose Hurren, Kika Anyiwe, Xinliang Mao, Fernando Suárez, Marcela Gronda, Yanina Eberhard, Neil MacLean, Troy Ketela, John C. Reed, Jason Moffat, Mark D. Minden, Robert A. Batey, Aaron D. Schimmer
Format: Artigo
Language:English
Published: 2010
Online Access:https://doi.org/10.1158/1535-7163.mct-09-0495
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https://doi.org/10.1158/1535-7163.mct-09-0495

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