HCV core protein interaction with gC1q receptor inhibits Th1 differentiation of CD4+ T cells via suppression of dendritic cell IL-12 production

Abstract Dendritic cells (DCs) isolated from patients with chronic hepatitis C virus (HCV) infection display an impaired capacity to generate type 1 CD4+ T cell immunity. Several reports have described an immunomodulatory function for the HCV core protein, and circulating core has been shown to asso...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Stephen N. Waggoner, Caroline Hall, Young S. Hahn
Médium: Artigo
Jazyk:angličtina
Vydáno: 2007
On-line přístup:https://doi.org/10.1189/jlb.0507268
https://academic.oup.com/jleukbio/article-pdf/82/6/1407/49638063/jlb1407.pdf
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!