HCV core protein interaction with gC1q receptor inhibits Th1 differentiation of CD4+ T cells via suppression of dendritic cell IL-12 production
Abstract Dendritic cells (DCs) isolated from patients with chronic hepatitis C virus (HCV) infection display an impaired capacity to generate type 1 CD4+ T cell immunity. Several reports have described an immunomodulatory function for the HCV core protein, and circulating core has been shown to asso...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Acesso em linha: | https://doi.org/10.1189/jlb.0507268 https://academic.oup.com/jleukbio/article-pdf/82/6/1407/49638063/jlb1407.pdf |
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