HCV core protein interaction with gC1q receptor inhibits Th1 differentiation of CD4+ T cells via suppression of dendritic cell IL-12 production

Abstract Dendritic cells (DCs) isolated from patients with chronic hepatitis C virus (HCV) infection display an impaired capacity to generate type 1 CD4+ T cell immunity. Several reports have described an immunomodulatory function for the HCV core protein, and circulating core has been shown to asso...

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Main Authors: Stephen N. Waggoner, Caroline Hall, Young S. Hahn
Format: Artigo
Jezik:angleščina
Izdano: 2007
Online dostop:https://doi.org/10.1189/jlb.0507268
https://academic.oup.com/jleukbio/article-pdf/82/6/1407/49638063/jlb1407.pdf
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