Highly Functionalized Terpyridines as Competitive Inhibitors of AKAP–PKA Interactions

Highly Functionalized Terpyridines as Competitive Inhibitors of AKAP–PKA Interactions

A good fit: Interactions between A-kinase anchoring proteins (AKAPs) and protein kinase A (PKA) play key roles in a plethora of physiologically relevant processes whose dysregulation causes or is associated with diseases such as heart failure. Terpyridines have been developed as α-helix mimetics for...

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Bibliografische gegevens
Hoofdauteurs: Gesa Schäfer, Jelena Milić, Adeeb El‐Dahshan, Frank Götz, Kerstin Zühlke, Christian Schillinger, Annika Kreuchwig, Jonathan M. Elkins, K.R. Abdul Azeez, Andreas Oder, Marie Christine Moutty, Nanako Masada, Monika Beerbaum, Brigitte Schlegel, Sylvia Niquet, Peter Schmieder, Gerd Krause, Jens Peter von Kries, Dermot M.F. Cooper, Stefan Knapp, Jörg Rademann, Walter Rosenthal, Enno Klußmann
Formaat: Artigo
Taal:Engels
Gepubliceerd in: 2013
Online toegang:https://doi.org/10.1002/anie.201304686
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https://doi.org/10.1002/anie.201304686

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