Brain-Derived Neurotrophic Factor Produces Antidepressant Effects in Behavioral Models of Depression

Previous studies demonstrated that antidepressant treatment increases the expression of brain-derived neurotrophic factor (BDNF) in rat hippocampus. The present study was conducted to test the hypothesis that BDNF in the hippocampus produces an antidepressant effect in behavioral models of depressio...

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Bibliographic Details
Main Authors: Yukihiko Shirayama, Andrew C. H. Chen, Shin Nakagawa, David Russell, Ronald S. Duman
Format: Artigo
Language:English
Published: 2002
Online Access:https://doi.org/10.1523/jneurosci.22-08-03251.2002
https://www.jneurosci.org/content/jneuro/22/8/3251.full.pdf
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