Polycomb- and REST-associated histone deacetylases are independent pathways toward a mature neuronal phenotype
The bivalent hypothesis posits that genes encoding developmental regulators required for early lineage decisions are poised in stem/progenitor cells by the balance between a repressor histone modification (H3K27me3), mediated by the Polycomb Repressor Complex 2 (PRC2), and an activator modification...
Na minha lista:
| Principais autores: | , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
|
| Acesso em linha: | https://doi.org/10.7554/elife.04235 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|