Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres

Survivin, a subunit of the chromosome passenger complex (CPC), binds the N-terminal tail of histone H3, which is phosphorylated on T3 by Haspin kinase, and localizes the complex to the inner centromeres. We used x-ray crystallography to determine the residues of Survivin that are important in bindin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: E. Niedzialkowska, Fangwei Wang, Przemyslaw Porebski, W. Minor, Jonathan M.G. Higgins, P. Todd Stukenberg
Fformat: Artigo
Iaith:Saesneg
Cyhoeddwyd: 2012
Mynediad Ar-lein:https://doi.org/10.1091/mbc.e11-11-0904
Tagiau: Ychwanegu Tag
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