Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres
Survivin, a subunit of the chromosome passenger complex (CPC), binds the N-terminal tail of histone H3, which is phosphorylated on T3 by Haspin kinase, and localizes the complex to the inner centromeres. We used x-ray crystallography to determine the residues of Survivin that are important in bindin...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | inglese |
| Pubblicazione: |
2012
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| Accesso online: | https://doi.org/10.1091/mbc.e11-11-0904 |
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