Segregation of non-p.R132H mutations in<i>IDH1</i>in distinct molecular subtypes of glioma

Segregation of non-p.R132H mutations in<i>IDH1</i>in distinct molecular subtypes of glioma

Mutations in the gene encoding the isocitrate dehydrogenase 1 gene (IDH1) occur at a high frequency (up to 80%) in many different subtypes of glioma. In this study, we have screened for IDH1 mutations in a cohort of 496 gliomas. IDH1 mutations were most frequently observed in low grade gliomas with...

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Detaylı Bibliyografya
Asıl Yazarlar: Lonneke A.M. Gravendeel, Nanne K. Kloosterhof, Linda B.C. Bralten, Ronald van Marion, Hendrikus J. Dubbink, Winand N.M. Dinjens, Fonnet E. Bleeker, Casper C. Hoogenraad, Erna Michiels, Johan M. Kros, Martin J. van den Bent, Peter A.E. Sillevis Smitt, Pim J. French
Materyal Türü: Artigo
Dil:İngilizce
Baskı/Yayın Bilgisi: 2010
Online Erişim:https://doi.org/10.1002/humu.21201
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/humu.21201
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Internet

https://doi.org/10.1002/humu.21201
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/humu.21201

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