Posttranscriptional Control of the Stem Cell and Neurogenic Programs by the Nonsense-Mediated RNA Decay Pathway
The mechanisms dictating whether a cell proliferates or differentiates have undergone intense scrutiny, but they remain poorly understood. Here, we report that UPF1, a central component in the nonsense-mediated RNA decay (NMD) pathway, plays a key role in this decision by promoting the proliferative...
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| Main Authors: | , , , , , , |
|---|---|
| Format: | Artigo |
| Language: | English |
| Published: |
2014
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| Online Access: | https://doi.org/10.1016/j.celrep.2014.01.028 |
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