Lipopolysaccharide Induces Disseminated Endothelial Apoptosis Requiring Ceramide Generation
The endotoxic shock syndrome is characterized by systemic inflammation, multiple organ damage, circulatory collapse and death. Systemic release of tumor necrosis factor (TNF)-α and other cytokines purportedly mediates this process. However, the primary tissue target remains unidentified. The present...
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Main Authors: | , , , , , , , , , |
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格式: | Artigo |
语言: | 英语 |
出版: |
1997
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在线阅读: | https://doi.org/10.1084/jem.186.11.1831 https://rupress.org/jem/article-pdf/186/11/1831/1683160/97-1132.pdf |
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