Lipopolysaccharide Induces Disseminated Endothelial Apoptosis Requiring Ceramide Generation

The endotoxic shock syndrome is characterized by systemic inflammation, multiple organ damage, circulatory collapse and death. Systemic release of tumor necrosis factor (TNF)-α and other cytokines purportedly mediates this process. However, the primary tissue target remains unidentified. The present...

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Main Authors: Adriana Haimovitz–Friedman, Carlos Cordón-Cardo, Shariff Bayoumy, Mark Garzotto, Maureen McLoughlin, Ruth Gallily, Carl K. Edwards, Edward H. Schuchman, Zvi Fuks, Richard Kolesnick
Format: Artigo
Jezik:angleščina
Izdano: 1997
Online dostop:https://doi.org/10.1084/jem.186.11.1831
https://rupress.org/jem/article-pdf/186/11/1831/1683160/97-1132.pdf
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