Abrogated transforming growth factor beta receptor II (TGFβRII) signalling in dendritic cells promotes immune reactivity of T cells resulting in enhanced atherosclerosis

The importance of transforming growth factor beta (TGFβ) as an immune regulatory cytokine in atherosclerosis has been established. However, the role of TGFβ signalling in dendritic cells (DCs) and in DC-mediated T cell proliferation and differentiation in atherosclerosis is unknown. Here, we investi...

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Main Authors: Dirk Lievens, Kim L. L. Habets, Anna-Karin Robertson, Yasmina Laouar, Holger Winkels, Timo Rademakers, Linda Beckers, Erwin Wijnands, Louis Boon, Munir M. Mosaheb, Hafid Ait‐Oufella, Ziad Mallat, Richard A. Flavell, Mats Rudling, Christoph J. Binder, Norbert Gerdes, Erik A.L. Biessen, Christian Weber, Mat J.A.P. Daemen, Johan Kuiper, Esther Lutgens
格式: Artigo
语言:英语
出版: 2012
在线阅读:https://doi.org/10.1093/eurheartj/ehs106
https://academic.oup.com/eurheartj/article-pdf/34/48/3717/17353939/ehs106.pdf
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