Inactivation of the mitotic checkpoint as a determinant of the efficacy of microtubule-targeted drugs in killing human cancer cells

Abstract Drugs that disrupt microtubule dynamics include some of the most important of cancer chemotherapies. While these drugs, which include paclitaxel (Taxol), are known to invoke the mitotic checkpoint, the factors that determine cancer cell killing remain incompletely characterized. Cells that...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Eric A. Lee, Michael K. Keutmann, Melissa L. Dowling, Eleanor Harris, Gordon K. Chan, Gary D. Kao
Hōputu: Artigo
Reo:Ingarihi
I whakaputaina: 2004
Urunga tuihono:https://doi.org/10.1158/1535-7163.661.3.6
https://aacrjournals.org/mct/article-pdf/3/6/661/1868193/661-669.pdf
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