Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas
Inflammatory hepatocellular adenomas (IHCAs) are benign liver tumors. 60% of these tumors have IL-6 signal transducer (IL6ST; gp130) mutations that activate interleukin 6 (IL-6) signaling. Here, we report that 12% of IHCA subsets lacking IL6ST mutations harbor somatic signal transducer and activator...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Acesso em linha: | https://doi.org/10.1084/jem.20110283 https://rupress.org/jem/article-pdf/208/7/1359/1206543/jem_20110283.pdf |
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