Human Immunodeficiency Virus Type 1 V1-V2 Envelope Loop Sequences Expand and Add Glycosylation Sites over the Course of Infection, and These Modifications Affect Antibody Neutralization Sensitivity

ABSTRACT Over the course of infection, human immunodeficiency virus type 1 (HIV-1) continuously adapts to evade the evolving host neutralizing antibody responses. Changes in the envelope variable loop sequences, particularly the extent of glycosylation, have been implicated in antibody escape. To do...

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Hlavní autoři: Manish Sagar, Xueling Wu, Charles Lee, Julie Overbaugh
Médium: Artigo
Jazyk:angličtina
Vydáno: 2006
On-line přístup:https://doi.org/10.1128/jvi.00141-06
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