Human Immunodeficiency Virus Type 1 V1-V2 Envelope Loop Sequences Expand and Add Glycosylation Sites over the Course of Infection, and These Modifications Affect Antibody Neutralization Sensitivity
ABSTRACT Over the course of infection, human immunodeficiency virus type 1 (HIV-1) continuously adapts to evade the evolving host neutralizing antibody responses. Changes in the envelope variable loop sequences, particularly the extent of glycosylation, have been implicated in antibody escape. To do...
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Glavni autori: | , , , |
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Format: | Artigo |
Jezik: | engleski |
Izdano: |
2006
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Online pristup: | https://doi.org/10.1128/jvi.00141-06 |
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