Inhibition of Mammalian Target of Rapamycin Reverses Alveolar Epithelial Neoplasia Induced by Oncogenic <i>K-ras</i>
Abstract The serine/threonine kinase AKT and its downstream mediator mammalian target of rapamycin (mTOR) are activated in lung adenocarcinoma, and clinical trials are under way to test whether inhibition of mTOR is useful in treating lung cancer. Here, we report that mTOR inhibition blocked maligna...
-д хадгалсан:
| Үндсэн зохиолчид: | , , , , , , , , , |
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| Формат: | Artigo |
| Хэл сонгох: | англи |
| Хэвлэсэн: |
2005
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| Онлайн хандалт: | https://doi.org/10.1158/0008-5472.can-04-4420 https://aacrjournals.org/cancerres/article-pdf/65/8/3226/2542217/3226-3235.pdf |
| Шошгууд: |
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