Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo

Cellular responses to both physiological and pathological DNA double-strand breaks are initiated through activation of the evolutionarily conserved ataxia telangiectasia mutated (ATM) kinase. Upon DNA damage, an activation mechanism involving autophosphorylation has been reported to allow ATM to pho...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: J. Daniel, Manuela Pellegrini, Ji‐Hoon Lee, Tanya T. Paull, Lionel Feigenbaum, André Nussenzweig
Hōputu: Artigo
Reo:Ingarihi
I whakaputaina: 2008
Urunga tuihono:https://doi.org/10.1083/jcb.200805154
https://rupress.org/jcb/article-pdf/183/5/777/1339781/jcb_200805154.pdf
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