Myostatin knockout drives browning of white adipose tissue through activating the AMPK‐PGC1α‐Fndc5 pathway in muscle
Myostatin (Mstn) is predominantly expressed in skeletal muscles and plays important roles in regulating muscle growth and development, as well as fat deposition. Mstn-knockout (Mstn(-/-)) mice exhibit increased muscle mass due to both hypertrophy and hyperplasia, and leaner body composition due to r...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Englisch |
| Veröffentlicht: |
2013
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| Online-Zugang: | https://doi.org/10.1096/fj.12-225755 |
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