The retinoblastoma protein induces apoptosis directly at the mitochondria
The retinoblastoma protein gene RB-1 is mutated in one-third of human tumors. Its protein product, pRB (retinoblastoma protein), functions as a transcriptional coregulator in many fundamental cellular processes. Here, we report a nonnuclear role for pRB in apoptosis induction via pRB's direct p...
में बचाया:
| मुख्य लेखकों: | , , , , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | अंग्रेज़ी |
| प्रकाशित: |
2013
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| ऑनलाइन पहुंच: | https://doi.org/10.1101/gad.211326.112 http://genesdev.cshlp.org/content/27/9/1003.full.pdf |
| टैग: |
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