Hutchinson–Gilford progeria syndrome through the lens of transcription

Lamins are nuclear intermediate filaments. In addition to their structural roles, they are implicated in basic nuclear functions such as chromatin organization, DNA replication, transcription, DNA repair, and cell-cycle progression. Mutations in human LMNA gene cause several diseases termed laminopa...

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Main Authors: Miron Prokocimer, Rachel Barkan, Yosef Gruenbaum
格式: Revisão
語言:英语
出版: 2013
在線閱讀:https://doi.org/10.1111/acel.12070
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/acel.12070
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