Hutchinson–Gilford progeria syndrome through the lens of transcription
Lamins are nuclear intermediate filaments. In addition to their structural roles, they are implicated in basic nuclear functions such as chromatin organization, DNA replication, transcription, DNA repair, and cell-cycle progression. Mutations in human LMNA gene cause several diseases termed laminopa...
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Hauptverfasser: | , , |
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Format: | Revisão |
Sprache: | Englisch |
Veröffentlicht: |
2013
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Online-Zugang: | https://doi.org/10.1111/acel.12070 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/acel.12070 |
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