A DNA hypermethylation module for the stem/progenitor cell signature of cancer
Many DNA-hypermethylated cancer genes are occupied by the Polycomb (PcG) repressor complex in embryonic stem cells (ESCs). Their prevalence in the full spectrum of cancers, the exact context of chromatin involved, and their status in adult cell renewal systems are unknown. Using a genome-wide analys...
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| Autors principals: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | anglès |
| Publicat: |
2012
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| Accés en línia: | https://doi.org/10.1101/gr.131169.111 http://genome.cshlp.org/content/22/5/837.full.pdf |
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