A DNA hypermethylation module for the stem/progenitor cell signature of cancer

Many DNA-hypermethylated cancer genes are occupied by the Polycomb (PcG) repressor complex in embryonic stem cells (ESCs). Their prevalence in the full spectrum of cancers, the exact context of chromatin involved, and their status in adult cell renewal systems are unknown. Using a genome-wide analys...

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Hoofdauteurs: Hariharan Easwaran, Sarah E. Johnstone, Leander Van Neste, Joyce E. Ohm, Tim Mosbruger, Qiuju Wang, Martin J. Aryee, Patrick F. Joyce, Nita Ahuja, Dan Weisenberger, Eric A. Collisson, Jingchun Zhu, Srinivasan Yegnasubramanian, William Matsui, Stephen B. Baylin
Formaat: Artigo
Taal:Engels
Gepubliceerd in: 2012
Online toegang:https://doi.org/10.1101/gr.131169.111
http://genome.cshlp.org/content/22/5/837.full.pdf
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