Adenosine A2A Receptors and A2A Receptor Heteromers as Key Players in Striatal Function

Adenosine A2A Receptors and A2A Receptor Heteromers as Key Players in Striatal Function

A very significant density of adenosine A(2A) receptors (A(2A)Rs) is present in the striatum, where they are preferentially localized postsynaptically in striatopallidal medium spiny neurons (MSNs). In this localization A(2A)Rs establish reciprocal antagonistic interactions with dopamine D(2) recept...

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Bibliographic Details
Main Authors: Sergi Ferré, César Quiroz, Marco Orrù, Xavier Guitart, Gemma Navarro, Antonio Cortés, Vicent Casadó, Enric I. Canela, Carme Lluı́s, Rafael Franco
Format: Artigo
Language:English
Published: 2011
Online Access:https://doi.org/10.3389/fnana.2011.00036
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https://doi.org/10.3389/fnana.2011.00036

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