Phosphorylation of Cardiac Myosin-Binding Protein-C Is a Critical Mediator of Diastolic Function

Phosphorylation of Cardiac Myosin-Binding Protein-C Is a Critical Mediator of Diastolic Function

Background— Heart failure (HF) with preserved ejection fraction (HFpEF) accounts for ≈50% of all cases of HF and currently has no effective treatment. Diastolic dysfunction underlies HFpEF; therefore, elucidation of the mechanisms that mediate relaxation can provide new potential targets for treatme...

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Главные авторы: Paola C. Rosas, Yang Liu, Mohamed I. Abdalla, Candice Thomas, David Kidwell, Giuseppina Dusio, Dhriti Mukhopadhyay, Rajesh Kumar, Kenneth M. Baker, Brett M. Mitchell, Patricia A. Powers, Daniel P. Fitzsimons, Bindiya Patel, Chad M. Warren, R. John Solaro, Richard L. Moss, Carl W. Tong
Формат: Artigo
Язык:английский
Опубликовано: 2015
Online-ссылка:https://doi.org/10.1161/circheartfailure.114.001550
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https://doi.org/10.1161/circheartfailure.114.001550

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