Structure and functional characterization of the atypical human kinase haspin
The protein kinase haspin/Gsg2 plays an important role in mitosis, where it specifically phosphorylates Thr-3 in histone H3 (H3T3). Its protein sequence is only weakly homologous to other protein kinases and lacks the highly conserved motifs normally required for kinase activity. Here we report stru...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | anglais |
| Publié: |
2009
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| Accès en ligne: | https://doi.org/10.1073/pnas.0901989106 |
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