CovR and VicRK Regulate Cell Surface Biogenesis Genes Required for Biofilm Formation in Streptococcus mutans

The two-component system VicRK and the orphan regulator CovR of Streptococcus mutans co-regulate a group of virulence genes associated with the synthesis of and interaction with extracellular polysaccharides of the biofilm matrix. Knockout mutants of vicK and covR display abnormal cell division and...

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Main Authors: Rafael Nóbrega Stipp, Heike Boisvert, Daniel J. Smıth, José Francisco Höfling, Margaret J. Duncan, Renata O. Mattos‐Graner
格式: Artigo
语言:英语
出版: 2013
在线阅读:https://doi.org/10.1371/journal.pone.0058271
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0058271&type=printable
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