CovR and VicRK Regulate Cell Surface Biogenesis Genes Required for Biofilm Formation in Streptococcus mutans
The two-component system VicRK and the orphan regulator CovR of Streptococcus mutans co-regulate a group of virulence genes associated with the synthesis of and interaction with extracellular polysaccharides of the biofilm matrix. Knockout mutants of vicK and covR display abnormal cell division and...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Englisch |
| Veröffentlicht: |
2013
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| Online-Zugang: | https://doi.org/10.1371/journal.pone.0058271 https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0058271&type=printable |
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