Transcription factors are required for the meiotic recombination hotspot at the HIS4 locus in Saccharomyces cerevisiae.
The full activity of a recombination initiation site located 5' of HIS4 requires the binding of the transcription factors RAP1, BAS1, and BAS2. Two RAP1 binding sites can substitute for the wild-type initiation site. A 51-bp region of telomeric DNA inserted upstream of either HIS4 or ARG4 very...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
1993
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| Online Access: | https://doi.org/10.1073/pnas.90.14.6621 |
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