Novel <i>Pseudomonas aeruginosa</i> Quorum-Sensing Inhibitors Identified in an Ultra-High-Throughput Screen
The opportunistic pathogen Pseudomonas aeruginosa has two complete acyl-homoserine lactone (acyl-HSL) signaling systems, LasR-LasI and RhlR-RhlI. LasI catalyzes the synthesis of N-3-oxododecanoyl homoserine lactone (3OC12-HSL), and LasR is a transcription factor that requires 3OC12-HSL as a ligand....
Furkejuvvon:
Váldodahkkit: | , , , , , |
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Materiálatiipa: | Artigo |
Giella: | eaŋgalasgiella |
Almmustuhtton: |
2006
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Liŋkkat: | https://doi.org/10.1128/aac.00665-06 |
Fáddágilkorat: |
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