Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs

Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs

Evidence of endoplasmic reticulum (ER) stress has been found in lungs of patients with familial and sporadic idiopathic pulmonary fibrosis. We tested whether ER stress causes or exacerbates lung fibrosis by ( i ) conditional expression of a mutant form of surfactant protein C (L188Q SFTPC ) found in...

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Hlavní autoři: William E. Lawson, Dong‐Sheng Cheng, Amber L. Degryse, Harikrishna Tanjore, Vasiliy V. Polosukhin, Xiaochuan Xu, Dawn C. Newcomb, Brittany R. Jones, Juan Roldán‐Merino, Kirk B. Lane, Edward E. Morrisey, Michael F. Beers, Fiona E. Yull, Timothy S. Blackwell
Médium: Artigo
Jazyk:angličtina
Vydáno: 2011
On-line přístup:https://doi.org/10.1073/pnas.1107559108
https://www.pnas.org/content/pnas/108/26/10562.full.pdf
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https://doi.org/10.1073/pnas.1107559108
https://www.pnas.org/content/pnas/108/26/10562.full.pdf

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