Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs
Evidence of endoplasmic reticulum (ER) stress has been found in lungs of patients with familial and sporadic idiopathic pulmonary fibrosis. We tested whether ER stress causes or exacerbates lung fibrosis by ( i ) conditional expression of a mutant form of surfactant protein C (L188Q SFTPC ) found in...
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| Autori principali: | , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | inglese |
| Pubblicazione: |
2011
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| Accesso online: | https://doi.org/10.1073/pnas.1107559108 https://www.pnas.org/content/pnas/108/26/10562.full.pdf |
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