Leptin Suppression of Insulin Secretion by the Activation of ATP-Sensitive K+ Channels in Pancreatic β-Cells

In the genetic mutant mouse models ob/ob or db/db, leptin deficiency or resistance, respectively, results in severe obesity and the development of a syndrome resembling NIDDM. One of the earliest manifestations in these mutant mice is hyperinsulinemia, suggesting that leptin may normally directly su...

Olles dieđut

Furkejuvvon:
Bibliográfalaš dieđut
Váldodahkkit: Timothy J. Kieffer, R. Scott Heller, Colin A. Leech, George G. Holz, Joel F. Habener
Materiálatiipa: Artigo
Giella:eaŋgalasgiella
Almmustuhtton: 1997
Liŋkkat:https://doi.org/10.2337/diab.46.6.1087
https://diabetesjournals.org/diabetes/article-pdf/46/6/1087/513065/46-6-1087.pdf
Fáddágilkorat: Lasit fáddágilkoriid
Eai fáddágilkorat, Lasit vuosttaš fáddágilkora!