Atg7 Induces Basal Autophagy and Rescues Autophagic Deficiency in CryAB <sup>R120G</sup> Cardiomyocytes
Rationale: Increasing evidence suggests that misfolded proteins and intracellular aggregates contribute to cardiac disease and heart failure. Several cardiomyopathies, including the αB-crystallin R120G mutation (CryAB R120G ) model of desmin-related cardiomyopathy, accumulate cytotoxic misfolded pro...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | 英語 |
| 出版事項: |
2011
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| オンライン･アクセス: | https://doi.org/10.1161/circresaha.110.237339 |
| タグ: |
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