β-Lactam Resistance in Methicillin-Resistant Staphylococcus aureus USA300 Is Increased by Inactivation of the ClpXP Protease
ABSTRACT Methicillin-resistant Staphylococcus aureus (MRSA) has acquired the mecA gene encoding a peptidoglycan transpeptidase, penicillin binding protein 2a (PBP2a), which has decreased affinity for β-lactams. Quickly spreading and highly virulent community-acquired (CA) MRSA strains recently emerg...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | anglais |
| Publié: |
2014
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| Accès en ligne: | https://doi.org/10.1128/aac.02802-14 |
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