Direct Repression of <i>FLIP</i> Expression by c-myc Is a Major Determinant of TRAIL Sensitivity
Tumor necrosis factor alpha (TNF-alpha)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF-alpha family of death receptor ligands and holds great therapeutic potential as a tumor cell-specific cytotoxic agent. Using a panel of established tumor cell lines and normal cells, we found a s...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | angličtina |
| Vydáno: |
2004
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| On-line přístup: | https://doi.org/10.1128/mcb.24.19.8541-8555.2004 |
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