Direct Repression of <i>FLIP</i> Expression by c-myc Is a Major Determinant of TRAIL Sensitivity

Tumor necrosis factor alpha (TNF-alpha)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF-alpha family of death receptor ligands and holds great therapeutic potential as a tumor cell-specific cytotoxic agent. Using a panel of established tumor cell lines and normal cells, we found a s...

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Príomhchruthaitheoirí: M. Ricci, Zhaoyu Jin, Michael Dews, Duonan Yu, Andrei Thomas‐Tikhonenko, David T. Dicker, Wafik S. El‐Deiry
Formáid: Artigo
Teanga:Béarla
Foilsithe / Cruthaithe: 2004
Rochtain ar líne:https://doi.org/10.1128/mcb.24.19.8541-8555.2004
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