R16, a novel amonafide analogue, induces apoptosis and G2-M arrest via poisoning topoisomerase II
Abstract Amonafide, a naphthalimide derivative, although selected for exploratory clinical trials for its potent anticancer activity, has long been challenged by its unpredictable side effects. In the present study, a novel amonafide analogue, 2-(2-dimethylamino)-6-thia-2-aza-benzo-[def]-chrysene-1,...
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| Główni autorzy: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | angielski |
| Wydane: |
2007
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| Dostęp online: | https://doi.org/10.1158/1535-7163.mct-06-0584 https://aacrjournals.org/mct/article-pdf/6/2/484/1877474/484.pdf |
| Etykiety: |
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