Exome sequencing and functional analyses suggest that SIX6 is a gene involved in an altered proliferation–differentiation balance early in life and optic nerve degeneration at old age

Exome sequencing and functional analyses suggest that SIX6 is a gene involved in an altered proliferation–differentiation balance early in life and optic nerve degeneration at old age

Primary open-angle glaucoma (POAG) is a hereditary neurodegenerative disease, characterized by optic nerve changes including increased excavation, notching and optic disc hemorrhages. The excavation can be described by the vertical cup–disc ratio (VCDR). Previously, genome-wide significant evidence...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Adriana I. Iglesias, Henriët Springelkamp, Herma van der Linde, Lies‐Anne Severijnen, Najaf Amin, Ben A. Oostra, Christel Kockx, Mirjam C. G. N. van den Hout, Wilfred F. J. van IJcken, Albert Hofman, André G. Uitterlinden, Robert M. Verdijk, Caroline C. W. Klaver, Rob Willemsen, Cornelia M. van Duijn
Formato: Artigo
Lenguaje:inglés
Publicado: 2013
Acceso en línea:https://doi.org/10.1093/hmg/ddt522
https://academic.oup.com/hmg/article-pdf/23/5/1320/14142472/ddt522.pdf
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doi.org/10.1093/hmg/ddt522
https://academic.oup.com/hmg/article-pdf/23/5/1320/14142472/ddt522.pdf

Ejemplares similares