Inflammation stimulates niacin receptor (GPR109A/HCA2) expression in adipose tissue and macrophages

Many of the beneficial and adverse effects of niacin are mediated via a G protein receptor, G protein-coupled receptor 109A/hydroxycarboxylic acid 2 receptor (GPR109A/HCA2), which is highly expressed in adipose tissue and macrophages. Here we demonstrate that immune activation increases GPR109A/HCA2...

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Библиографические подробности
Главные авторы: Kenneth R. Feingold, Arthur H. Moser, Judy K. Shigenaga, Carl Grünfeld
Формат: Artigo
Язык:английский
Опубликовано: 2014
Online-ссылка:https://doi.org/10.1194/jlr.m050955
http://www.jlr.org/content/55/12/2501.full.pdf
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